Friday, 30 September 2016

The Journey Through a Cell - Packaged and Ready to Go

 So we're back in the Golgi Apparatus, where lots of little things occur.

For us, a tiny little protein, visiting the Golgi Apparatus is an important part of our journey, where there are folds called "cisternae". Here, in the Golgi Apparatus, we are modified after entering the cis face and then packaged into little membranous sacs called vesicles, upon leaving the trans face.

[Source: http://www.buzzle.com]

These vesicles are perfect for storage and transport, and contain a single membrane with fluid inside.

Now we're all packaged comfortably into our vesicle, we'll journey again through the cytoskeleton

[Source: cellspd5spering.wikispaces.com]

We're all ready, but how do we escape the cell?

Stay tuned!

- Geeker

The Journey Through a Cell - It's Just the Beginning

Since I've been very busy with studies recently, I thought I'd show you some of my work.

So here's some A-Level Biology!

The Journey Through a Cell - It's Just the Beginning

 

We begin in the nucleus - where all our genetic information as chromatin (containing DNA and histones) is condensed into chromosomes. Inside here we've also got the nucleolus, which is responsible for making RNA molecules and ribosome. We've got a surrounding nuclear envelope, and small nuclear pores - allowing only certain molecules to pass in and out of the nucleus. So let's say we're an RNA molecule, after being made in the nucleolus we pass through the nuclear pores...


 Our next stop is at the endoplasmic reticulum, where there are two types:

  • Smooth Endoplasmic Reticulum
  • Rough Endoplasmic Reticulum
Now, you might be asking how tiny organelles can be "rough". Well, the smooth endoplasmic reticulum (SER) is responsible for carbohydrate and lipid synthesis. However, the rough endoplasmic reticulum (RER) which is where we're heading, contains many ribosomes on its surface - making it rough.  These ribosomes are the main site for protein synthesis, so it turns our small RNA body into a protein.



After venturing through the SER, we hop into the tracks of the "Cytoskeleton" which is responsible for many different things. It's made up of three components:

  • Microfilaments  - Contractile actin fibres which are responsible for cell contraction and cytokinesis
  • Intermediate fibres - for strength and integrity of the cell
  • Microtubules - (which is where we're heading) for not only a component in spindle fibres, but also "tracks" for transport of molecules within a cell. 
"Actin filaments are shown in red, and microtubules composed of beta tubulin are in green."

Now we travel down to the "golgi apparatus"

What happens next? Stay tuned for more!


- Geeker